Is Your Diet Bad for Your Brain?

We are facing a new pandemic. Not the result of a return of Covid or bird flu but caused by something much closer to home that affects us every day. The food we eat. It is damaging our brain.

A report, just published in the Lancet, found that neurological diseases, from autism to Alzheimer’s, are affecting 43% of the world’s population. The Federation of European Neuroscientists have declared a ‘brain health emergency’. The Times reports that two thirds of benefit claims are for mental health. Diagnoses of autism and ADHD are steadily increasing.

The good news is that a fightback is beginning.

Yesterday a virtual “Upgrade Your Brain” conference, organised by the charitable foodforthebrain.org, brought together leading neuroscientists –  psychiatrists, nutritionists and neurologists from around the world –  to brainstorm the cause and a solution. They identified the four ‘horsemen of the mental health apocalypse’ lurking in our diet.

Standard healthy eating advice rarely warns about them all. They are:

  • A lack of brain fats, notably omega-3 from seafood but also vitamin D
  • Increased intake of sugar and ultra-processed foods
  • A lack of the many antioxidants and polyphenols (micronutrients) found in spices, vegetables and fruits, especially berries
  • Lack of B vitamins, notably B12, producing homocysteine, a brain toxic amino acid

 

The toll exacted by the horsemen is vast. Mental illness is now costing considerably more than all cancer and heart disease combined. “The Children’s Society recently reported a tripling in NHS referrals for mental ill-health in the last three years.” says Professor Michael Crawford, at the Chelsea and Westminster Hospital Campus of Imperial College.

According to Crawford the damage begins in pregnancy. Lack of B12 and folate in the mother increases later behavioural problems in their children. Fewer than 5 per cent of children get the basic recommendation of seafood rich in omega-3 and many eat none at all. “Special schools are bursting at the seams,” says Dr Rona Tutt, former president of the National Association of Head Teachers.

“High sugar and ultra-processed foods is devastaing mental health and plays a major part in the increase in both ADHD, depression and dementia.” says Professor Robert Lustig from the University of California. Dr Georgia Ede, a psychiatrist from Harvard, reports low carb diets reversing mental illness.

According to the NHS one in five adults in England are on anti-depressants and last year one million teenagers were prescribed them. This year prescriptions are expected to exceed 100 million. Independent researchers have been warning about their lack of effectiveness and damaging side-effects.

But it is not just nutritional deficiencies that are threatening our brains. The way we live can contribute to the damage “The combination of poor diet, lack of exercise, less intellectual and social stimulation, stress and insomnia creates a ‘perfect storm’ for the brain,” says neuroscientist Dr Tommy Wood at the University of Washington.

Wood is leading research at the charity foodforthebrain.org, which has developed a defensive strategy to protect the brain with nutritional and lifestyle changes. It starts by finding out just how well your brain is doing via a free online Cognitive Function Test followed up by personalised advice on how to reduce your dementia risk,

The fourth horseman, high homocysteine (a consequence of a lack of B vitamins) is linked to all of the mental problems that are on the rise because it damages nerves and brain cells as well as arteries, the supply chain for the brain. If your homocysteine is high, which it is in half of those over 65, your memory is declining. Lowering it reduces brain shrinkage in those with pre-dementia by two thirds according to Oxford University research. GP’s rarely test it.

Testing and lowering homocysteine is a key target of the charity’s prevention plan. Participants are sent a home test kit to measure blood levels of omega-3, homocysteine, HBA1c for sugar balance and vitamin D, lack of which is another contributor to dementia and depression. The charity aims to reach a million people in the largest ever ‘citizen science’ project and have tested 420,000 so far.

The idea that Alzheimer’s can be prevented is gaining support. The US National Institutes of Health have attributed 22% of the risk of Alzheimer’s to raised blood homocysteine and 22% to a lack of seafood and omega-3 fats.

A recent study using UK Biobank data concluded that up to 72% of dementia cases could be prevented if all risk factors were targeted. “Even this is probably under-estimating the power of prevention.” says Professor David Smith from the University of Oxford, one of the study authors. “The number of preventable cases could be higher if a person’s omega-3 and B vitamin status, measured, by a blood test for homocysteine (not measured by the UK Biobank) were taken into account.” China’s leading prevention expert, Professor Jin-Tai Yu from Shanghai’s Fudan University, a co-author of this study, agrees. “Homocysteine-lowering treatment with vitamins, especially B12, is one of the most promising interventions for dementia prevention.”

What Next? Upgrade your Brain AND Become a Citizen Scientist

Thanks to already well over 400,000 ‘citizen scientists we have, with the sword of digital technology, opened the oyster to uncover the true causes – all under your control – that are driving this terrible and unnecessary brain shrinkage.

Those citizen scientists have taken the time, often initially for personal interest, to discover their actual cognitive function, and completed a comprehensive questionnaire.

We hope to reach a million people around the world within a year or so making this the biggest prevention-focussed study of its kind.

Change is not going to come from the Government or the NHS. It is going to have to come from us, the people.

We ask you to take control of upgrading your brain and in the process become Citizen Scientists for better brain health for future generations.

Follow these seven steps.

STEP 1: Take the Cognitive Function Test

What you’ll learn:

  • Find out where you are on the cognitive function scale
  • Learn the most important dietary and lifestyle actions you can take
  • Take control of your mental wellbeing
  • Contribute to the Food for the Brain research process

Take the Cognitive Function Test

STEP 2: Test for the Four Keystone Biochemical Processes

Get tested for the four keystone biochemical processes with the DRIfT Test.

It will calculate your Dementia Risk Index functional Test (DRIfT) score. Tracking this, along with your Cognitive Function (CFT) and Dementia Risk Index (DRI) is the most comprehensive way to protect your brain.

This 4-in-1 test measures:

  • Vitamin D
  • Omega-3
  • Homocysteine
  • HbA1C

More info – Drift Test from Food for the Brain and Other Tests.

STEP 3 – Get Educated

Read my book Upgrade Your Brain – Out Now!

More info & to order – Upgrade Your Brain Book

Join me on my UK or Ireland Seminar Tour – May/June

I’m visiting 30 cities in the UK and Ireland in May/June to kick start a nationwide ‘Upgrade Your Brain’ campaign.

“We need to engage with millions of people, get nutrition education happening in schools, and most of all get heath authorities and governments around the world to take the mental health meltdown seriously and put brain health at the top of the health agenda.”

Professor Crawford says “Today’s diet bears no resemblance to the wild foods we ate during our species’ evolution to which our genome is adapted. If we don’t prioritise brain health and nutrition the continued escalation of mental ill health, starting in the 1950s, can only end in disaster.”

Dates/locations: More tour info & how to book

Sign up to my E-News

Go to the home page of this website and sign up to my E-News for more blogs/reports/videos and podcasts on brain health. Follow on Facebook (PatrickHolford) and Instagram. (PatrickHolford.UK)

STEP 4: Start a Brain Healthy Diet

The Upgrade Your Brain cooking app with brain-friendly recipes will be launching soon. It will help you make the right food choices for your brain.

Pre-order the Brain Cook App. 

STEP 5: Ensure You Get Enough of the Right Nutrients

There are three essentials for building brain cells (neurons) – omega-3 fats, B vitamins and Phospholipids. Omega-3 is bound to phospholipids by methylation which is a process that is dependent on B vitamins – B6, B12 and folate.

There are some key supplements that have been identified to support brain health. In the Holford range these are:

  • Connect: B vitamins and zinc to support healthy methylation
  • High PC Lecithin – A Rich source of 63% phospholipid
  • Omega-3 Support – 550mg of DHA and 750mg of EPA

All these are found in the Brain Food Upgrade pack.

STEP 6: Spread the Word & Promote Prevention

We urge everyone share the ‘prevention’ message with others.

You can do this by sharing social media posts and blogs/reports.

You can participate in Alzheimer’s Prevention Day on 15 May and encourage others to do the same. Take the free 3-minute online Alzheimer’s Prevention Check and get motivated to make the eight brain-friendly diet and lifestyle changes

“You are the architect of your own brain’s future health.” says neurologist Dr David Perlmutter.

Take the test for Alzheimer’s Prevention Day

Step 7: Support the ‘Prevention’ Work

‘Friends’ donate £50 a year and get so much in return. This is how we are funding our amazing research team (see foodforthebrain.org/researchteam/). We are a lean, keen, small but mighty team.

Every donation, big or small, goes right back into helping people prevent these preventable and terrible diseases such as dementia. Together, we can change the world. We need to, because time is running out. We will lose our humanity if we don’t stop this brain drain.”

All donations are put back into research, and the results of the research are shared back to people.

Give to Food for the Brain and support their work.