Low GL for Dementia Prevention

  • 25 Jun 2018
  • Reading time 2 mins
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A high GL diet creates advance-glycation end-products that have the capability of damaging the brain. The brain, more than any other organ, is dependent on a steady supply of glucose. Growing evidence links high GL diets with increasing risk of dementia and memory loss. Thew GL of a diet is more predictive than GI or quantity of carbs. Clinical trials testing the effects of a low GL diet are lacking.

STUDY 1

A study in the US finds modest increase in blood sugar levels meant an 18%
increased risk of dementia. Those with diabetes had a 40 per cent increased
risk.

Crane, P et al. New England Journal of Medicine (2013)

STUDY 2

Twice as many people with high insulin levels developed dementia. People with the highest insulin had the worst memory.

J. A. Luchsinger, et al., Neurology, 2004

STUDY 3

An Italian study shows the link between increasing insulin and worsening mental function.

A. M. Abbatecola, et al. Journal of American Geriatric Society, 2004

STUDY 4

 A six-year Swedish study showed that those with diabetes were 1.5 times more likely to develop dementia.

 W. L. Xu, et al., Neurology, 2004

STUDY 5

In California University researchers reported that postmenopausal
women with HbA1C levels above 7 per were four times more likely to develop
dementia.

Yaffe, K, et al., Archives of Neurology, 2009

STUDY 6

A study in Puerto Rica shows that those in the top fifth of sugar consumption had double the risk of poor cognitive function.

Ye X et al., British Journal of Nutrition, 2011

STUDY 7

 A US study shows the GL of the diet most accurately predicted who would start to experience a decline in memory.

Seetharaman S et al., J Gerontol A Biol Sci Med Sci. 2015

STUDY 8

Irish study finds the GL of a person’s diet, not GI or quantity of carbs, that most predicted decline in cognition.

Power S et al., European Journal of Nutrition, 2015

STUDY 9

The GL of one’s diet is more predictive of pathological
changes associated with Alzheimer’s.

Taylor M  et al., Am J Clin Nutr. 2017 Dec

STUDY 10

Brain shrinkage occurs even in high but ‘normal’ and
certainly common glucose levels.

Mortby, M et al. Cherbuin. PLoS One (2013)

STUDY 11

Cognitive decline in overweight children is associated with a high GL diet.

Lakhan, S. E. & A. Kirchgessner. Nutr J (2013)

 

 

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